LEI 11418 PDF

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Abstract Ginkgo biloba, an herbal medication, is capable of lowering glucose, fat, and lipid peroxide in diabetic patients.

Abstract Our aim is to investigate the potential therapeutic value of morin against osteoporosis and elucidate the mechanism of action. The relative expression of osteogenic and bone resorption markers was determined by real-time polymerase chain reaction and Western blotting, respectively. CitePeer Related Articles http: Either your web browser doesn’t support Javascript or it is currently turned off.

CitePeer Related Articles http: Journal of Eli Medicines [03 Sep65 1: Gene Ontology GO Terms. Body weight and BMD were both significantly decreased in osteoporotic rats, although BMD was partially restored by intraperitoneal morin administration. Find all citations in this journal default.

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The data indicated that GBE repressed glucose uptake under normal conditions, while it dramatically improved glucose tolerance under insulin-resistant conditions. It is said that GBE treatment could avoid drug-induced obesity.

Read Article at publisher’s site. Or filter your current search. Body weight was regularly monitored. We investigated the effects of GBE on glucose consumption, glucokinase activity, and mRNA levels of key genes in glucose metabolism and the insulin signaling pathway.

Either your web browser doesn’t support Javascript or it is currently turned off. No matching affiliation detected. Body mineral density BMD was eli at proximal femurs using dual energy X-ray absorptiometry. To better show its efficacy, we included a control group that was treated with rosiglitazone, a type of thiazolidinedione TZD.

Mechanistically, morin reversed the decrease of osteogenic markers and increase of bone resorption markers, which might eventually be mediated by modulation of MAPK signaling cascades. In the latter case, please turn on Javascript support in your web browser and reload this page.

Furthermore, after analyzing gene expression, we suggest that GBE chiefly exerts its effects by stimulating IRS-2 transcription. Or filter your current search. In the current study, we tested the hypothesis that Ginkgo biloba extract GBE prevented hyperinsulinism-induced glucose intolerance in hepatocytes.

Our data suggest that GBE has the potential to prevent insulin resistance and is a promising anti-diabetic drug. It should be noted that, unlike rosiglitazone, GBE did not stimulate excessive glucose uptake as it improved glucose tolerance. Pathological examination was performed by hematoxylin and eosin staining. Journal of Natural Medicines [24 Jul72 4: Gene Ontology GO Terms. Europe PMC requires Javascript to function effectively.

Find all citations in this journal default. In the latter case, please turn on Javascript support in your web browser and reload this page. Here, we uncovered the therapeutic effect of morin against osteoporosis and demonstrated its suppressive action on the MAPK pathway in this disease.

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How does Europe PMC derive its citations network? Read Article at publisher’s site. Morin treatment also increased the number of trabecular bones in DEX-induced rats. 111418 PMC requires Javascript to function effectively. How does Europe PMC derive its citations network?